Ex.plaura

Clinical Platform

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Precision Medicine + Neuroscience  

Our brain platform utilizes novel sensing technology, 3D mapping, and artificial intelligence to deepen our understanding of the brain and unlock personalized brain care

Interview with Dr. Sumeet Vadera

We Empower physicians to make the best possible treatment decisions

Dr. Vadera is a neurosurgeon at University of California, Irvine (“UCI”) Health who specializes in both adult and paediatric epilepsy and uses a range of surgical technologies including robot-assisted intra-cranial surgery.

How it Works

SENSING

Intracranial Electrodes

We are developing minimally invasive, flexible, and light-weight sensors for recording high-resolution EEG activity

 

Propriety thin-film electrode technology and novel depth / hybrid design to drastically improves surgical implantation and minimize brain tissue damage

 NEURAURA ADVANTAGE

  • Shorter surgery times and faster patient recovery

  • Improved brain coverage

  • High fidelity EEG data for rapid and easy diagnoses and precise treatments

  • Reduced clinical burden and healthcare costs

  • Cortical electrodes: grid and strip electrodes

  • Subdural electrodes: depth electrodes for use with anchor bolts for stereo-EEG

  • Hybrid electrodes: novel proprietary design combining cortical micro-strips with depth electrodes

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RECORDING

Wireless EEG Monitoring

Hardware for continuous recording of brain activity​ 

 

Transmits the sensor data to the recording unit wirelessly

NEURAURA ADVANTAGE

  • Better patient experience by enabling portable care at-home or in-hospital

  • Ability to collect "real-life data"

  • Reduced hospital costs

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DIAGNOSING

3D Brain Mapping

Visualization software that presents the brain data traces and displays a 3D map of the electrical activity within the brain

NEURAURA ADVANTAGE

  • Cloud-based storage to access the brain data anywhere, anytime

  • Accelerated clinician review of data

  • Greater surgical and treatment confidence

  • Unlocks personalized brain care and neuromodulation treatments

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Epilepsy as an Initial Clinical Application

Epilepsy is one of the most common neurological conditions, affecting approximately 1% of the world population. 

 

For 1/3 of patients, the drugs are not effective.  It has been medically proven that surgery is the best option for most of these patients.  However, a limited number of epilepsy surgeries are conducted each year due to the lack of high quality data required for successful surgery and the difficult / risky patient journey.

Epilepsy patients undergo intra-cranial monitoring as part of the protocol for surgical resection of brain tissue to treat seizures.  These patients are often therefore the subjects of research into the electrical workings of the brain.

Neuraura will gain access to unique electrophysiological data sets from epilepsy patients where there is the potential for transformational impact across disease states and treatment modalities based on advancing our understanding of the electrical workings of the brain. 

We are devoted to enhancing the surgical process, optimizing patient outcomes, and deepening our understanding of the brain

Clinical Applications

Epilepsy

Migraine

Stroke

Alzheimer's
Disease (AD)

Psychiatry

Parkinson's
Disease (PD)

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